Liu Laboratory

Publications

2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010-2000 1999-1979

2022

Tosoni S, Huynh Q, Murphy P, Habal F, Musing E, Hodges B, Liu FF. Physician Champions of Quality and Safety: Perspectives of MD Quality and Safety Leads to Drive Quality Innovation at an Academic Hospital. Healthcare Quarterly. 2022 Jan;24(4):48-53.
Mushonga M, Kwan JYY, Purdie TG, Chaulk G, DeRocchis J, Munhoz RP, Leong WL, Hodaie M, Liu FF. Deep Brain Stimulators and Radiation Therapy in Cancer Patients. Clin Oncol (R Coll Radiol). 2022 Jan 4:S0936-6555(21)00515-X.

2021

Burgener J, Zou J, Zhao Z, Zheng Y, Shen SY, Huang SH, Keshavarzi S, Xu W, Liu FF, Liu G, Waldron JN, Weinreb I, Spreafico A, Siu LL, de Almeida JR, Goldstein DP, Hoffman MM, DeCarvalho DD, Bratman SV. Tumor-naive multimodal profiling of circulating tumor DNA in head and neck squamous cell carcinoma. Clin Cancer Res. 2021 Jun 22:clincanres.CCR-21-0110-A.2021.
Fijardo M, Bissey PA, Yip K, Liu FF. miRNA biomarkers for NPC diagnosis and prognosis. ANPC. 2021 Jun 30;5:3.
Psarianos P, Kwan JYY, Dell S, Wee WB, Rey-McIntyre K, Chen H, Dissanayake D, Laxer RM, Shum A, Liu FF, Yip KW. COPA Syndrome (Ala239Pro) Presenting with Isolated Follicular Bronchiolitis in Early Childhood: Case Report. J Clin Immunol. 2021 Jun 11.
Bruce JP, To KF, Lui VWY, Chung GTY, Chan YY, Tsang CM, Yip KY, Ma B, Woo J, Hui E, Mak M, Lee SD, Chow C, Velapasamy S, Or YYY, Siu PK, Ghamrasni SE, Prokopec S, Wu M, Kwan J, Liu Y, Chan JYK, van Hasselt A, Young L, Dawson CW, Paterson I, Yap LF, Tsao SW, Liu FF, Chan A, Pugh T, Lo KW. Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape. Nat Commun. 2021 May 19.
Reiazi R, Abbas E, Famiyeh P, Rezaie A, Kwan JYY, Patel T, Bratman SV, Tadic T, Liu FF, Haibe-Kains B. The impact of the variation of imaging parameters on the robustness of Computed Tomography radiomic features: A review. Comput Biol Med. 2021 Apr 16;133:104400.
Harnett N, Tosoni S, Brandt C, Ito E, Milne E, Liu FF, Wong R. Accelerated Education Program in Radiation Medicine: International Learner Perceptions of Experiences, Outcomes, and Impact. Int J Radiat Oncol Biol Phys. 2021 Mar 1;109(3):656-660.
Kwan JYY, Lin LT, Bell R, Bruce JP, Richardson C, Pugh TJ, Liu FF. Elevation in viral entry genes and innate immunity compromise underlying increased infectivity and severity of COVID-19 in cancer patients. Sci Rep. 2021 Feb 25;11(1):4533.
Tosoni S, Voruganti I, Lajkosz K, Habal F, Murphy P, Wong RKS, Willison D, Virtanen C, Heesters A, Liu FF. The use of personal health information outside the circle of care: consent preferences of patients from an academic health care institution. BMC Med Ethics. 2021 Mar 24;22(1):29.
Patel PS, Vyravanathan S, Milne E, Bezjak A, Wouters BG, Bennewith K, Seuntjens J, Liu ZA, Harding SM, Liu FF, Koritzinsky M, Koch CA. Strategic Training in Transdisciplinary Radiation Science for the 21st Century (STARS21): 15-Year Evaluation of an Innovative Research Training Program. Int J Radiat Oncol Biol Phys. 2021 Jan 10:S0360-3016(21)00023-7.

2020

Kwan JYY, Famiyeh P, Su J, Xu W, Kwan BYM, Jones JM, Chang E, Yip KW, Liu FF. Development and Validation of a Risk Model for Breast Cancer-Related Lymphedema. JAMA Netw Open. 2020;3(11):e2024373.
Shi W, Misra S, Li M, Su J, Chong LP, McCuske M, Williams J, Xu W, Ghoraie LS, Sutherland DR, Han K, Minden MD, Bratman SV, Yip KW, Liu FF. Inflammatory Biomarkers, Hematopoietic Stem Cells, and Symptoms in Breast Cancer Patients Undergoing Adjuvant Radiation Therapy. JNCI Cancer Spectr. 2020 May 8;4(5):pkaa037.
Ito E, Moraes FY, Ramotar M, Lunsky I, Soliman H, Catton CN, Kassam Z, Morton G, Tosoni S, Gospodarowicz M, Wong RKS, Liu FF, Chung PWM. Radiation Oncology Fellowship: a Value-Based Assessment Among Graduates of a Mature Program. J Cancer Educ. 2020 Jul 18.
Madariaga A, McMullen M, Sheikh S, Kumar R, Liu FF, Zimmermann C, Husain S, Zadeh G, Oza AM. COVID-19 testing in cancer patients: Does one size fit all? Clin Cancer Res. 2020 Jul 2..
Bissey PA, Teng M, Law JH, Shi W, Bruce JP, Petit V, Sai TW, Yip KW, Liu FF. MiR-34c Downregulation Leads to SOX4 Overexpression and Cisplatin Resistance in Nasopharyngeal Carcinoma. BMC Cancer. 2020 Jun 26;20(1):597.
Koch CA, Lee G, Liu ZA, Liu F-F, Fyles A, Han K, Barry A, Croke J, Rodin D, Helou J, Hahn E, Isfahanian N, DeRoccis J, Lofgren S, Purdie T. Rapid adaptation of breast radiotherapy utilization during the COVID-19 pandemic at a large academic cancer centre in Canada. Adv Radiat Oncol. 2020 Jun 2.
Keilty D, Namini SN, Swain M, Maganti M, Cil TD, McCready DR, Cescon DW, Amir E, Fleming R, Mulligan AM, Fyles A, Croke JM, Liu FF, Levin W, Koch CA, Han K. Patterns of recurrence and predictors of survival in breast cancer patients treated with neoadjuvant chemotherapy, surgery, and radiation. Int J Radiat Oncol Biol Phys. 2020 May 11.
O’Sullivan B, Huang SH, Keane T, Xu W, Su J, Waldron J, Gullane P, Liu FF, Warde P, Payne D, Tong L, Cummings B. Durable Therapeutic Gain despite Competing Mortality in Long-term Follow-up of a Randomized Hyperfractionated Radiotherapy Trial for Locally Advanced Head and Neck Cancer. Clin Transl Radiat Oncol. 2020 Jan 28;21:69-76.
Zhao X, Kwan JYY, Yip K, Liu PP, Liu FF. Targeting metabolic dysregulation for fibrosis therapy. Nat Rev Drug Discov. 2020 Jan;19(1):57-75.

2019

Hall SF, Griffiths RJ, O'Sullivan B, Liu FF. The addition of chemotherapy to radiotherapy did not reduce the rate of distant metastases in low-risk HPV-related oropharyngeal cancer in a real-world setting. Head Neck. 2019 Jul; 41(7): 2271–2276.
Loudon J, Proctor L, Wenz J, Roussos J, Chaudhry N, Moseley D, Zhang B, Yeung I, Liu FF, Wells W. Development of a Collaboration Model between Two Cancer Centres to Maintain Patient Access to Radiation Therapy during the Replacement of a Sole CT Simulator at a Regional Cancer Centre. J Med Imaging Radiat Sci. 2019 Jun;50(2):206-211.
Lee S, Cabanero M, Hyrcza M, Butler MO, Liu FF, Hansen A, Huang SH, Tsao M, Song Y, Lu L, Xu W, Chepeha D, Goldstein D, Weinreb I, Bratman S. Computer-Assisted Image Analysis of the Tumor Microenvironment on an Oral Tongue Squamous Cell Carcinoma Tissue Microarray. Clin Transl Radiat Oncol. 2019 May 18;17:32-39.
Kwan JYY, Croke J, Panzarella T, Ubhi K, Fyles A, Koch A, Dinniwell R, Levin W, McCready D, Chung C, Liu F, Bender JL. Personalizing post-treatment cancer care: a cross-sectional survey of the needs and preferences of well survivors of breast cancer. Curr Oncol. 2019 Apr;26(2):e138-e146.
Beeler WH, Griffith KA, Jones RD, Chapman CH, Holliday EB, Lalani N, Wilson E, Bonner JA, Formenti SC, Hahn SM, Kalnicki S, Liu FF, Movsas B, Thomas CR Jr, Jagsi R. Gender, Professional Experiences, and Personal Characteristics of Academic Radiation Oncology Chairs: Data to Inform the Pipeline for the 21st Century. Int J Radiat Oncol Biol Phys. 2019 Jan 23. pii: S0360-3016(19)30156-7.
Zhao X, Psarianos P, Ghoraie LS, Yip K, Goldstein D, Gilbert R, Witterick I, Pang H, Hussain A, Lee JH, Williams J, Bratman SV, Ailles L, Haibe-Kains B, Liu FF. Metabolic regulation of dermal fibroblasts contributes to skin extracellular matrix homeostasis and fibrosis. Nat Metab. 2019 Jan 7;1:147-157.

2018

Inoue M, Nakashima R, Enomoto M, Koike Y, Zhao X, Yip K, Huang SH, Waldron JN, Ikura M, Liu FF, Bratman SV. Plasma redox imbalance caused by albumin oxidation promotes lung-predominant NETosis and pulmonary cancer metastasis. Nat Commun. 2018 Nov 30;9(1):5116.
Karamboulas C, Bruce JP, Hope AJ, Meens J, Huang SH, Erdmann N, Pereira K, Goldstein DP, Weinreb I, Su J, O’Sullivan B, Tiedemann R, Liu FF, Pugh TJ, Bratman SV, Xu W, Ailles L. Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma. Cell Reports. Cell Rep. 2018 Oct 30;25(5):1318-1331.e4.
Demidov V, Zhao X, Demidova O, Pang HYM, Flueraru C, Liu FF, Vitkin IA. Preclinical quantitative in-vivo assessment of skin tissue vascularity in radiation-induced fibrosis with optical coherence tomography. J Biomed Opt. 2018 Oct;23(10):1-9.
Su B, Xu T, Bruce JP, Yip KW, Zhang N, Huang Z, Zhang G, Liu FF, Liang J, Yang H, Claret FX. hsa-miR-24 suppresses metastasis in nasopharyngeal carcinoma by regulating the c-Myc/epithelial-mesenchymal transition axis. Oncol Rep. 2018 Nov; 40(5): 2536–2546.
Principe S, Mejia-Guerrero S, Ignatchenko V, Sinha A, Ignatchenko A, Shi W, Pereira K, Su S, Huang SH, O'Sullivan B, Xu W, Goldstein D, Weinreb I, Ailles, Liu FF, Kislinger T. Proteomic Analysis of Cancer Associated Fibroblasts Reveal a Paracrine Role for MFAP5 in Human Oral Tongue Squamous Cell Carcinoma. J Proteome Res. 2018 Jun 1;17(6):2045-2059.
Bissey PA, Law JH, Bruce JP, Shi W, Renoult A, Chua MLK, Yip KW, Liu FF. Dysregulation of the MiR-449b target TGFBI alters the TGFβ pathway to induce cisplatin resistance in nasopharyngeal carcinoma. Oncogenesis. 2018 May 22;7(5):40.
Ahmed MM, Mendonca MS, Bentzen SM, Vikram B, Seltzer S, Goodhead DT, Obcemea C, Mohan R, Prise KM, Capala J, Citrin DE, Kao GD, Aryankalayil MJ, Liu FF, Buchsbaum JC, Prasanna PG, Eke I, Le QT, Teicher BA, Kirsch DG, Smart DK, Tepper JE, Formenti SC, Haas-Kogan D, Raben D, Mitchell JB, Coleman CN. Defining the Shades of Gy: Utilizing the Biological Consequences of Radiation Therapy in the Development of New Treatment Approaches. Cancer Res. 2018 May 1;78(9):2166-2170.
Jones RD, Chapman CH, Holliday EB, Lalani N, Wilson E, Bonner JA, Movsas B, Kalnicki S, Formenti SC, Thomas CR Jr., Hahn SM, Liu FF, Jagsi R; Society of Chairs of Academic Radiation Oncology Programs (SCAROP). Qualitative Assessment of Academic Radiation Oncology Department Chairs' Insights on Diversity, Equity, and Inclusion: Progress, Challenges, and Future Aspirations. Int J Radiat Oncol Biol Phys. 2018 May 1;101(1):30-45.

2017

Hamilton JL, Foxcroft S, Moyo E, Cooke-Lauder J, Spence T, Zahedi P, Bezjak A, Jaffray D, Lam C, Létourneau D, Milosevic M, Tsang R, Wong R, Liu FF. Strategic planning in an academic radiation medicine program. Curr Oncol. 2017 Dec;24(6):e518-e523.
Hall SF, Liu FF, O’Sullivan B, Shi W, Rohland S, Griffiths R, Groome P. Did the addition of concurrent chemotherapy to conventional radiotherapy improve survival for patients with HPV+ve and HPV-ve Oropharynx cancer? A population-based study. Br J Cancer. 2017 Oct 10;117(8):1105-1112.
Chhin V, Roussos J, Michaelson T, Bana M, Bezjak A, Foxcroft S, Hamilton JL, Liu FF. Leveraging mobile technology to improve efficiency of the consent-to-treatment process. JCO Clin Cancer Inform. 2017 Sep 12; (1):1-8.
Holliday EB, Bonner JA, Formenti SC, Hahn SM, Kalnicki S, Liu FF, Movsas B, Fuller CD, Thomas CR. Emotional Intelligence and Burnout in Academic Radiation Oncology Chairs. J Healthc Manag. 62(5):302-313, 2017.
Dovlo E, Lashkari B, Soo Sean Choi S, Mandelis A, Shi W, Liu FF, Quantitative phase-filtered wavelength-modulated differential photoacoustic radar tumor hypoxia imaging toward early cancer detection. J Biophotonics. 10(9):1134-1142, 2017.
Bratman SV, Milosevic MF, Liu FF, Haibe-Kains B. Genomic biomarkers for precision radiation medicine. Lancet Oncol. 18(5):e238, 2017.
Bruce JP, Xu W, Liu FF. The KRAS Variant as a Predictive Biomarker of Cetuximab Response in Head and Neck Cancer . JAMA Oncol. 3(4):491-492, 2017.
Roussos J, Zahedi P, Spence T, Swanson LA, Li-Cheung F, Cops F, Darcy P, Chhin V, Moyo E, Warde P, Foxcroft S, Liu FF. Optimizing computed tomography simulation wait times in a busy radiation medicine program. Pract Radiat Oncol. 7(1):e77-e83, 2017.
Kinoshita T, Yip KW, Spence T, Liu FF. MicroRNAs in extracellular vesicles: potential cancer biomarkers. J Hum Genet. 62(1):67-74, 2017.

2016

Lee G, Dinniwell R, Liu FF, Fyles A, Han K, Conrad T, Levin W, Marshall A, Purdie TG, Koch CA. Building a New Model of Care for Rapid Breast Radiotherapy Treatment Planning: Evaluation of the Advanced Practice Radiation Therapist in Cavity Delineation. Clin Oncol (R Coll Radiol). 28(12):e184-e19, 2016.
Han K, Yap ML, Yong JH, Mittmann N, Hoch JS, Fyles AW, Warde P, Gutierrez E, Lymberiou T, Foxcroft S, Liu FF. Omission of Breast Radiotherapy in Low-risk Luminal A Breast Cancer: Impact on Health Care Costs. Clin Oncol (R Coll Radiol). 28(9):587-93, 2016.
Spence T, Bruce J, Yip KW, Liu FF. HPV Associated Head and Neck Cancer . Cancers. 8(8):e75, 2016.
Wang JR, Habbous S, Espin-Garcia O, Chen D, Huang SH, Simpson C, Xu W, Liu FF, Brown DH, Gilbert RW, Gullane PJ, Irish JC, Goldstein DP, Liu G. Comorbidity and performance status as independent prognostic factors in patients with head and neck squamous cell carcinoma . Head Neck. 38(5):736-42, 2016.
Vishnubalaji R, Hamam R, Yue S, Al-Obeed O, Kassem M, Liu FF, Aldahmash A, Alajez NM. MicroRNA-320 suppresses colorectal cancer by targeting SOX4, FOXM1, and FOXQ1 . Oncotarget. 7(24):35789-802, 2016.
Bratman SV, Bruce JP, O'Sullivan B, Pugh TJ, Xu W, Yip KW, Liu FF. Human Papillomavirus genotype association with survival in head and neck squamous cell carcinoma . JAMA Oncol. 2(6):823-6, 2016.
Spence T, Bruce JP, Yip KW, Liu FF. MicroRNAs in nasopharyngeal carcinoma . Chin Clin Oncol. 5(2):17, 2016.
Kwan JY, Psarianos P, Bruce JP, Yip KW, Liu FF. The complexity of microRNAs in human cancer . J Rad Res. 57:i106-11, 2016.
Shi W, Bruce J, Lee M, Yue S, Rowe M, Pintilie M, Kogo R, Bissey PA, Fyles A, Yip KW, Liu FF. MiR-449a promotes breast cancer progression by targeting CRIP2 . Oncotarget. 7(14):18906-18, 2016.
Haider S, Waggott D, Lalonde E, Fung C, Liu FF, Boutros PC. A bedr way of genomic interval processing. Source Code Biol Med. 11:14, 2016.
Vishnubalaji R, Yue S, Alfayez M, Kassem M, Liu FF, Aldahmash A, Alajez NM. Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells. Cancer Cell Int. 16:77, 2016.
Chu KP, Habbous S, Kuang Q, Boyd K, Mirshams M, Liu FF, Espin-Garcia O, Xu W, Goldstein D, Waldron J, O'Sullivan B, Huang SH, Liu G. Socioeconomic status, human papillomavirus, and overall survival in head and neck squamous cell carcinomas in Toronto, Canada. Cancer Epidemiol. 40:102-12, 2016.

2015

Wong P, Hui A, Su J, Yue S, Haibe-Kains B, Gokgoz N, Xu W, Bruce J, Williams J, Catton C, Wunder JS, Andrulis IL, Gladdy R, Dickson B, O'Sullivan B, Liu FF. Prognostic microRNAs modulate the RHO adhesion pathway: A potential therapeutic target in undifferentiated pleomorphic sarcomas. Oncotarget. 6(36):39127-39, 2015.
Bruce JP, Yip K, Bratman SV, Ito E, Liu FF. Nasopharyngeal cancer: Molecular landscape. J Clin Oncol. 33(29):3346-55, 2015.
Whelan TJ, Olivotto IA, Parulekar WR, Ackerman I, Chua BH, Nabid A, Vallis KA, White JR, Rousseau P, Fortin A, Pierce LJ, Manchul L, Chafe S, Nolan MC, Craighead P, Bowen J, McCready DR, Pritchard KI, Gelmon K, Murray Y, Chapman JA, Chen BE, Levine MN. Regional nodal irradiation in early-stage breast cancer. N Engl J Med. 373(4):307-16, 2015.
Thomas CR Jr, Bonner JA, Hahn SM, Lawrence TS, Liu FF, Formenti SC. Society of Chairs of Academic Radiation Oncology Programs-Endorsed Radiation Oncology Department Review Process. Int J Radiat Oncol Biol Phys. 92(3):536-9, 2015.
Liu FF, Shi W, Done SJ, Miller N, Pintilie M, Voduc D, Nielsen TO, Nofech-Mozes S, Chang MC, Whelan TJ, Weir LM, Olivotto IA, McCready DR, Fyles AW. Identification of a low-risk luminal A breast cancer cohort that may not benefit from breast radiotherapy. J Clin Oncol. 33(18):2035-40, 2015.
Formenti SC, Bonner JF, Hahn SM, Lawrence TS, Liu FF, Thomas CR Jr. Raising the next generation of physician-scientists: the chairs' perspective. Int J Radiat Oncol Biol Phys. 92(2):211-3, 2015.
How C, Bruce J, So J, Pintilie M, Haibe-Kains B, Hui A, Clarke BA, Hedley DW, Hill RP, Milosevic M, Fyles A, Liu FF. Chromosomal instability as a prognostic marker in cervical cancer. BMC Cancer. 15:361, 2015.
Wong P, Hui A, Su J, Yue S, Haibe-Kains B, Gokgoz N, Xu W, Bruce J, Williams J, Catton C, Wunder JS, Andrulis IL, Gladdy R, Dickson B, O'Sullivan B, Liu FF. Prognostic microRNAs modulate the RHO adhesion pathway: A potential therapeutic target in undifferentiated pleomorphic sarcomas. Oncotarget. [Epub ahead of print], 2015.
Huang SH, Xu W, Waldron J, Siu L, Shen X, Tong L, Ringash J, Bayley A, Kim J, Hope A, Cho J, Giuliani M, Hansen A, Irish J, Gilbert R, Gullane P, Perez-Ordonez B, Weinreb I, Liu FF, O'Sullivan B. Refining American Joint Committee on Cancer/Union for International Cancer Control TNM stage and prognostic groups for human papillomavirus-related oropharyngeal carcinomas. J Clin Oncol. 33(8):836-45, 2015.
Dovlo E, Lashkari B, Mandelis A, Shi W, Liu FF. Photoacoustic radar phase-filtered spatial resolution and co-registered ultrasound image enhancement for tumor detection. Biomedical Optics Express. 6(3):1003-1009, 2015.
Lymberiou T, Galuszka S, Lee G, Xu W, Fyles A, Su S, Purdie TG, Catton P, Chung C, Dinniwell R, Koch A, Levin W, Manchul L, Warde P, Liu FF. Predictors of breast radiotherapy plan modifications: Quality assurance rounds in a large cancer centre. Radiother Oncol. 114:17-21, 2015.
Cancer Genome Atlas Network. Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature. 517(7536):576-82, 2015.
Huang SH, Waldron JN, Milosevic M, Shen X, Ringash J, Su J, Tong L, Perez-Ordonez B, Weinreb I, Bayley A, Kim J, Hope A, Cho J, Giuliani M, Razak A, Goldstein D, Shi W, Liu FF, Xu W, O'Sullivan B. Prognostic value of pretreatment circulating neutrophils, monocytes, and lymphocytes in oropharyngeal cancer stratified by HPV status. Cancer. 121(4):545-55, 2015.
Sepiashvili L, Bruce J, Huang SH, O’Sullivan B, Liu FF, Kislinger T. Novel insights into head and neck cancer using next-generation "omic" technologies. Cancer Res. 75(3):480-486, 2015.
Kogo R, How C, Chaudary N, Bruce J, Shi W, Hill RP, Zahedi P, Yip KW, Liu FF. The microRNA-218~survivin axis regualtes migration, invasion, and lymph node metastasis in cervical cancer. Oncotarget. 6(2):1090-100, 2015.
Bruce JP, Hui ABY, Shi W, Perez-Ordonez B, Weinreb I, Xu W, Haibe-Kains B, Waggott DM, Boutros PC, O’Sullivan B, Waldron J, Huang SH, Chen EX, Gilbert R, Liu FF. Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma. Oncotarget. In Press, 2015.

2014

Huang SH, Xu W, Waldron J, Siu L, Shen XW, Tong L, Ringash J, Bayley A, Kim J, Hope A, Cho J, Giuliani M, Hansen A, Irish J, Gilbert R, Gullane P, Perez-Ordonez B, Weinreb I, Liu FF, O’Sullivan B. Refining UICC TNM stage and prognostic groups for non-metastatic HPV-related oropharyngeal carcinoma. J Clin Oncol. In Press, 2014.
Sepiashvili L, Waggott D, Hui A, Shi W, Su S, Ignatchenko A, Ignatchenko V, Laureano M, Huang SH, Xu W, Weinreb I, Waldro J, O’Sullivan B, Irish JC, Boutros PC Liu FF, Kislinger T. Integrated omic analysis of oropharyngeal carcinomas reveals HPV-dependent regulation of the AP-1 pathway. Mol Cell Proteomics.13(12):3572-82, 2014.
Weinreb I, Piscuoglio S, Martelotto LG, Waggot ,D, Ng CKY, Perez-Ordonez B, Harding NJ, Alfaro J, Chu KC, Viale A, Fusco N, DA Cruz Paula A, Machio C, Sakr RA, Lim R, Thompson LDR, Chiosea SI, Seethala RR, Skalova A, Stelow EB, Fonseca I, Assaad A, How C, Wang J, de Borja R, Chan-Seng-Yue M, Howlett CJ, Nichols AC, Wen YH, Katabi N, Buchner N, Mullen L, Kislinger T, Wouters BG, Liu FF, Norton L, McPherson JD, Rubin BP, Clarke BA, Weigelt B, Boutros PC, Reis-Filho JS. Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands. Nat Genet. 46(11):1166-9, 2014.
Coleman CN, Formenti SC,Williams TR, Petereit DC, Soo KC,Wong J, Chao N, Shulman LN,Grover S,Magrath I,Hahn S, Liu F-F,DeWeese T, Khleif S, Steinberg M, Roth L, Pistenmaa DA, Love RR, Mohiuddin M and Vikram B. The international cancer expert corps: a unique approach for sustainable cancer care in low and lower-middle income countries. Front Oncol. 4:333, 2014.
Weinreb I, Zhang L, Tirunagari LM, Sung YS, Chen LC, Perez-Ordonez B, Clarke BA, Skalova A, Chiosea SI, Seethala RR, Waggott D, Boutros PC, How C, Liu FF, Irish JC, Goldstein DP, Gilbert R, Ud Din N, Assaad A, Hornick JL, Thompson LD, Antonescu CR. Novel PRKD gene rearrangements and variant fusions in cribriform adenocarcinoma of salivary gland origin. Genes Chrom Cancer. 53(10):845-856, 2014.
Williams JP, Kim I, Ito E, Shi W, Yue S, Siu LL, Waldron J, O’Sullivan B, Yip KW, Liu FF. Pre-clinical characterization of dacomitinib (PF-00299804), an irreversible pan-ErbB inhibitor, combined with ionizing radiation for head and neck squamous cell carcinoma. PLoS One. 9(5):e98557, 2014.
Yip KW, Zhang Z, Sakemura-Nakatsugawa N, Huang JW, Vu NM, Chiang YK, Lin Cl, Kwan JYY, Yue S, Jitkova Y, To T, Zahedi P, Pai EF, Schimmer AD, Lovell JF, Sessler JL, Liu FF. A Porphodimethene Chemical Inhibitor of Uroporphyrinogen Decarboxylase. PLOS ONE. 9(2):e89889, 2014.

2013

Huang X, Taeb S, Jahangiri S, Emmenegger U, Tran E, Bruce J, Mesci A, Korpela E, Vesprini D, Wong CS, Bristow RG, Liu FF, Liu SK. miRNA-95 mediates radioresistance in tumors by targeting the sphingolipid phosphatase SGPP1. Cancer Res. 73(23):6972-86, 2013.
Wang JR, Gramling SJ, Goldstein DP, Cheng D, Chen D, Azad AK, Tse A, Hon H, Chen Z, Mirshams M, Simpson C, Huang SH, Marquez S, O’Sullivan B, Liu FF, Roberts H, Xu W, Brown DH, Gilbert RW, Gullane PJ, Irish JC, Reisman DN, Liu G. Association of two BRM promoter polymorphisms with head and neck squamous cell carcinoma risk. Carcinogenesis. 34(5):1012-1017, 2013.
Liu FF, Okunieff P, Bernhard EJ, Stone HB, Yoo SS, Coleman CN, Vikram B, Brown JM, Buatti JM, Guha C. Lessons learned from radiation oncology clinical trials. Clin Cancer Res.19(22):6089-100, 2013.
Chung GT, Lung RW, Hui AB, Yip KY, Woo JK, Chow C, Tong CY, Lee SD, Yuen JW, Lun SW, Tso KK, Wong N, Tsao SW, Yip TT, Busson P, Kim H, Seo JS, O’Sullivan B, Liu FF, To KF, Lo KW. Identification of a recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma. J Pathol. 231(2):158-67, 2013.
Lenarduzzi M,Y Hui AB, Yue S, Ito E, Shi W, Williams J, Bruce J, Sakemura-Nakatsugawa1 N, Xu W, Qiu X, Schimmer A, Liu FF. Hemochromatosis Enhances Tumor Progression via Upregulation of Intracellular Iron in Head & Neck Cancer. PLOS ONE. 8(1):e53765, 2013.
How C, Hui AB, Alajez NM, Shi W, Boutros PC, Clarke BA, Yan R, Pintilie M, Fyles A, Hedley DW, Hill RP, Milosevic M, Liu FF. MicroRNA-196b Regulates the Homeobox B7-Vascular Endothelial Growth Factor Axis in Cervical Cancer. PLOS ONE. 8(7): e67846, 2013.
Liu FF, Fyles A, Liu P. Low risk of cardiac events post-breast cancer radiotherapy. New England Journal of Medicine. 368(26):2523-2527, 2013.
Habbous S, Harland LT, La Delfa A, Fadhel E, Xu W, Liu FF, Goldstein D, Waldron J, Huang SH, O-Sullivan B, Liu G. Comorbidity and prognosis in head and neck cancers: Differences by subsite, stage, and human papillomavirus status. Head & Neck. In Press, 2013.
Principe S, Hui A, Bruce J, Sinha A, Liu FF, Kislinger T. Tumor-derived exosomes and microvesicles in head and neck cancer: implications for tumor biology and biomarker discovery. Proteomics. 13(10-11):1608-23, 2013.
O'Sullivan B, Huang SH, Siu LL, Waldron J, Zhao H, Perez-Ordonez B, Weinreb I, Kim J, Ringash J, Bayley A, Dawson LA, Hope A, Cho J, Irish J, Gilbert R, Gullane P, Hui A, Liu FF, Chen E, Xu W. Deintensification candidate subgroups in human papillomavirus-related oropharyngeal cancer according to minimal risk of distant metastasis. J Clin Oncol. 31(5):543-550, 2013.
Wang JR, Gramling SJ, Goldstein DP, Cheng D, Chen D, Azad AK, Tse A, Hon H, Chen Z, Mirshams M, Simpson C, Huang SH, Marquez S, O’Sullivan B, Liu FF, Roberts H, Xu W, Brown DH, Gilbert RW, Gullane PJ, Irish JC, Reisman DN, Liu G. Association of two BRM promoter polymorphisms with head and neck squamous cell carcinoma risk. Carcinogenesis. 34(5):1012-1017, 2013.
Lenarduzzi M, Hui AB, Alajez NM, Shi W, Williams J, Yue S, O’Sullivan B, Liu FF. MicroRNA-193b enhances tumor progression via down regulation of neurofibromin 1. PLoS One. 8(1) :e53765, 2013.
Huang SH, Perez-Ordonez B, Weinreb I, Hope A, Massey C, Waldron JN, Kim J, Bayley AJ, Cummings B, John Cho BC, Ringash J, Dawson LA, Siu LL, Chen E, Irish J, Gullane P, Hui A, Liu FF, Shen X, Xu W, O’Sullivan B. Natural course of distant metastases following radiotherapy or chemoradiotherapy in HPV-related oropharyngeal cancer. Oral Oncol. 49(1):79-85, 2013.
Hui AB, Lin A, Xu W, Waldron L, Perez-Ordonez B, Weinreb I, Shi W, Bruce J, Huang SH, O’Sullivan B, Waldron J, Gullane P, Irish JC, Chan K, Liu FF. Potentially prognostic miRNAs in HPV-associated oropharyngeal carcinoma. Clin Cancer Res. 19(8):2154-2162, 2013.

2012

Friborg J, Hamilton-Therkildsen M, Homoe P, Kristensen C, Hui A, Liu FF, Weinreb I. A spectrum of basaloid morphology in a subset of EBV-associated “lymphoepithelial carcinomas” of major salivary glands. Head Neck Pathol. 6(4):445-450, 2012.
Habbous S, Pang V, Eng L, Xu W, Kurtz G, Liu FF, Mackay HJ, Amir E, Liu G. p53 Arg72Pro polymorphism, HPV status and initiation, progression, and development of cervical cancer: a systematic review and meta-analysis. Clin Cancer Res. 18(23):6407-6415, 2012.
Sepiashvili L, Hui A, Ignatchenko V, Shi W, Su S, Xu W, Huang SH, O’Sullivan B, Waldron J, Irish JC, Perez-Ordonez B, Liu FF, Kislinger T. Potentially novel candidate biomarkers for head and neck squamous cell carcinoma identified using an integrated cell line-based discovery strategy. Mol Cell Proteomics. 11(11):1404-1415, 2012.
P’ng C, Ito E, How C, Bezjak A, Bristow R, Catton P, Fyles A, Gospodarowicz M, Jaffray D, Kelley S, Wong S, Liu FF. Excellence in Radiation Research for the 21st Century (EIRR21): description of an innovative research training program. Int J Radiat Oncol Biol Phys. 83:e563-70, 2012.
Sivachandran N, Dawson CW, Young LS, Liu FF, Middeldorp J, Frappier L. Contributions of the Epstein-Barr virus EBNA1 protein to gastric carcinoma. J Virol. 86(1):60-68, 2012.
Wang W, Purdie TG, Rahman M, Marshall A, Liu FF, Fyles A. Rapid automated treatment planning process to select breast cancer patients for active breathing control to achieve cardiac dose reduction. Int J Radiat Oncol Biol Phys. 82(1):386-393, 2012.
Huang SH, Perez-Ordonez B, Liu FF, Waldron J, Ringash J, Irish J, Cummings B, Siu LL, Kim J, Weinreb I, Hope A, Gullane P, Brown D, Shi W, O’Sullivan B. Atypical clinical behavior of p16-confirmed HPV-related oropharyngeal squamous cell carcinoma treated with radical radiotherapy. Int J Radiat Oncol Biol Phys. 82(1):276-283, 2012.
Teh AY, Walsh L, Purdie TG, Mosseri A, Xu W, Levin W, Koch CA, Fyles A, Liu FF, Cho BC. Concomitant intensity modulated boost during whole breast hypofractionated radiotherapy – A feasibility and toxicity study. Radiother Oncol. 102(1):89-95, 2012.
Alajez NM, Mocanu JD, Krushel T, Bell JC, Liu FF. Enhanced vesicular stomatitis virus (VSVΔ51) targeting of head and neck cancer in combination with radiation therapy or ZD6126 vascular disrupting agent. Cancer Cell Int. 12(1):27, 2012.
Waggott D, Chu K, Yin S, Wouters BG, Liu FF, Boutros PC. NanoStringNorm: an extensible R package for the pre-processing of NanoString mRNA and miRNA data. Bioinformatics. 28(11):1546-1548, 2012.
O’Sullivan B, Huang SH, Perez-Ordonez B, Massey C, Siu LL, Weinreb I, Hope A, Kim J, Bayley AJ, Cummings B, Ringash J, Dawson LA, Cho BC, Chen E, Irish J, Gilbert RW, Hui A, Liu FF, Zhao H, Waldron JN, Xu W. Outcomes of HPV-related oropharyngeal cancer patients treated by radiotherapy alone using altered fractionation. Radiother Oncol. 103(1):49-56, 2012.
Alajez NM, Shi W, Wong D, Lenarduzzi M, Waldron J, Weinreb I, Liu FF. Lin28b promotes head and neck cancer progression via modulation of the insulin-like growth factor survival pathway. Oncotarget. 3(12):1641-1652, 2012.

2011

Huang Q, Li F, Liu X, Li W, Shi W, Liu FF, O’Sullivan B, He Z, Peng Y, Tan AC, Zhou L, Shen J, Han G, Wang XJ, Thorburn J, Thorburn A, Jimeno A, Raben D, Bedford JS, Li CY. Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy. Nat Med. 17:860-6, 2011.
Ito E, Yue S, Moriyama E, Kim I, Hui A, Shi W, Alajez N, Bhogal N, Li GH, Datti A, Schimmer A, Liu P, Durocher D, Neel B, O’Sullivan B, Cummings B, Bristow R, Liu FF. Uroporphyrinogen decarboxylase is a radiosensitizing target for head and neck cancer. Science Translational Medicine. 3:67ra7, 2011.
Alajez N, Biswas D, Sutherland R, Pintilie M, Minden M, Messner H, Fyles A, Gospodarowicz M, Liu FF. The effect of local radiotherapy on circulating CD34+ cells in breast cancer patients. Rad Oncol. 100:304-307, 2011.
Alajez N, Lenarduzzi M, Ito E, Hui A, Shi W, Bruce J, Yue S, Huang SH, Xu W, Waldron J, O’Sullivan B, Liu FF. MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway. Cancer Res. 71:2381-2391, 2011.
Shi W, Gerster K, Alajez N, Tsang J, Waldron L, Pintilie M, Hui A, Sykes J, P’ng C, Miller N, McCready D, Fyles T, Liu FF. Micro-RNA 301 mediates proliferation and invasion in human breast cancer. Cancer Res. 71:2926-2937, 2011.
Hui A, Bruce JP, Alajez N, Shi W, Yue W, Perez-Ordonez B, Xu W, O’Sullivan B, Waldron J, Cummings B, Gullane P, Siu L, Liu FF. Significance of dysregulated metadherin and miR-375 in head & neck cancer. Cl Cancer Res. 17:7539-7550, 2011.
Walsh L, Guha D, Purdie TG, Bedard P, Easson A, Liu FF, Hodaie M. Spinal cord stimulators and radiotherapy: first case report and practice guidelines. Radiat Oncol. 25(6):143, 2011.
Ito E, Yip K, Liu FF. Uroporphyrinogen decarboxylase: Optimizing radiotherapy for head and neck cancer. Future Oncol. 7(5):595-597, 2011.
Hui A, How C, Ito E, Liu FF. Micro-RNAs as diagnostic or prognostic markers in human epithelial malignancies. BMC Cancer. 11:500, 2011.

2010-2000

Alajez N, Hui A, Shi W, Ito E, Yue S, Ng R, O’Sullivan B, Liu FF. Enhancer of Zeste Homologue 2 (EZH2) is over-expressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98. Cell Death & Dis. 1:e85, 2010.
Shi W, Alajez N, Bastianutto C, Hui A, Mocanu J, Ito E, Busson P, Lo K-W, Ng R, Waldron J, O’Sullivan B, Liu FF. Significance of PLK1 regulation by miR-100 in human nasopharyngeal cancer. Int J Cancer. 126:2036-48, 2010.
Gerster K, Shi W, Ng B, Waldron J, Gilbert R, Liu FF. Targeting PLK1 enhances radiation efficacy for head & neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 77(1):253-260, 2010.
Kato H, Ito E, Shi W, Alajez N, Yue S, Lee C, Chan N, Bhogal N, Vines D, Green D, Waldron J, Gullane P, Bristow R, Liu FF. Efficacy of combining GMX1777 with radiation therapy for human head and neck carcinoma. Cl Cancer Res. 16(3):898-911, 2010.
Hui A, Lenarduzzi M, Kushel T, Waldron L, Pintilie M, Shi W, Perez-Ordonez B, Jurisica I, O’Sullivan B, Waldron J, Gullane P, Cummings B, Liu FF. Comprehensive MicroRNA profiling for head and neck squamous cell carcinomas. Cl Cancer Res. 16(4):1129-39, 2010.
Razak ARA, Siu LL, Liu FF, Ito E, O’Sullivan B, Chan K. Nasopharyngeal carcinoma: The next challenges. Eur J Cancer. 46(11):1967-78, 2010.
Katz D, Ito E, Liu FF. On the path to seeking novel radiosensitizers. Int J Radiat Oncol Biol Phys. 73(4):988-996, 2009.
Sufan R, Linus A, Moriyama E, Evans A, Alajez N, Vitkin A, Yang V, Liu FF, Wilson B, Ohh M. Oxygen-independent degradation of HIF-α via bioengineered VHL tumour suppressor complex. EMBO Mol Med. 1(1):66-78, 2009.
Hui A, Shi W, Boutros P, Miller N, Pintilie M, Fyles A, McCready D, Wong D, Gerster K, Jurisica I, Penn L, Liu FF. Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues. Lab Invest. 89(5):597-606, 2009.
Hui A, Yue S, Shi W, Alajez N, Ito E, Green SR, Frame S, O’Sullivan B, Liu FF. Therapeutic efficacy of Seliciclib in combination with ionizing radiation for human nasopharyngeal carcinoma. Cl Cancer Res. 15: 3716-3724, 2009.
Alajez N, Shi W, Hui A, Ng R, Lo KW, Bastianutto C, O’Sullivan, Gullane P, Liu FF. Targeted depletion of BMI1 sensitizes tumor cells to P53-mediated apoptosis in response to radiation therapy. Cell Death & Diff. 16(11):1469-1479, 2009.
Shi W, Kato H, Perez-Ordonez B, Pintilie M, Huang S, Hui A, O’Sullivan B, Waldron J, Cummings BJ, Kim J, Ringash J, Dawson L, Gullane P, Siu LL, Gillison M, Liu FF. Comparative prognostic value of HPV16 E6 mRNA compared with in situ hybridization for human oropharyngeal squamous carcinoma. J Clin Oncol. 27(36): 6213-6221, 2009.
Yang H, Hui A, Pampalakis G, Soleymani L, Liu FF, Sargent E, Kelley SO. Direct, electronic microRNA detection for the rapid determination of differential expression profiles. Angewandte Chemie. 48(45): 8461-8464, 2009.
Moselhy J, Vira T, Liu FF, Wu XY. Characterization of complexation of poly(NIPAM/DMAEMAQ) thermoresponsive cationic nanogels with salmon sperm DNA. Int J Nanomedicine. 4: 153-64, 2009.
Ito E, Yip KW, Katz D, Hedley DW, Chow S, Xu W, Wood TE, Bastianutto C, Schimmer AD, Liu FF. Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer. Mol Pharmacol. 76(5):969-983, 2009.
Chia M, Leung A, Krushel T, Alajez N, Lo KW, Busson P, Klamut H, Bastianutto C, Liu FF. Nuclear factor-Y and Epstein Barr virus in nasopharyngeal cancer. Cl Cancer Res. 14(4):984-994, 2008.
Katz D, Ito E, Lau KS, Mocanu JD, Bastianutto C, Schimmer AD, Liu FF. Increased efficiency for performing colony formation assays in 96-well plates: novel applications to combination therapies and high-throughput screening. Biotechniques. 44(2):ix-xiv, 2008.
Waldron J, Warde P, Irish J, Pintilie M, Sellman S, Bayley A, Cummings BJ, Kim J, Liu FF, Payne D, Ringash J, Brown D, Freeman J, Gilbert R, Gullane P, Witterick I, O’Sullivan B. A dose escalation study of hyperfractionated accelerated radiation delivered with integrated neck surgery (HARDWINS) for the management of advanced head and neck cancer. Rad Oncol. 87(2):173-180, 2008.
Alajez N, Mocanu J, Shi W, Chia M, Breitbach CJ, Hui A, Knowles S, Bell J, Busson P, Takada K, Lo KW, O’Sullivan, Gullane P, Liu FF. Efficacy of systemically administered mutant Vesicular Stomatitis Virus (VSVdelta51) combined with radiation for nasopharyngeal carcinoma. Cl Cancer Res. 14(15):4891-4897, 2008.
Cummings BJ, Keane T, Pintilie M, Warde P, Waldron J, Payne D, Liu FF, Bissett R, McLean M, Gullane P, O’Sullivan B. Five year results of a randomized trial comparing hyperfractionated to conventional radiotherapy over four weeks in locally advanced head and neck cancer. Rad Oncol. 85(1):7-16, 2007.
Liu FF, Frappier L, Kim J, O’Sullivan, Hui A, Bastianutto C. East-West Symposium on nasopharyngeal cancer. Int J Radiat Oncol Biol Phys. 67(3):703-708, 2007.
Moselhy J, Sarkar S, Chia MC, Mocanu JD, Taulier N, Liu FF, Wu XY. Evaluation of copolymers of N-isopropylacrylamide and 2-dimethyl(aminoethyl)methacrylate in nonviral and adenoviral vectors for gene delivery to nasopharyngeal carcinoma. Int J Nanomedicine. 2(3):461-478, 2007.
Mocanu JD, Yip KW, Alajez H, Shi W, Li JH, Lunt SJ, Moriyama EH, Wilson BC, Milosevic M, Lo KW, van Rooijen N, Busson P, Bastianutto C, Liu FF. Imaging the modulation of adenoviral kinetics and biodistribution for cancer gene therapy. Mol Therapy. 15(5):921-9, 2007.
Liu FF. Nasopharyngeal cancer: New frontiers from the laboratory to the clinic. Int J Radia Oncol Biol Phys. 69(2 Suppl):S122-124, 2007.
Mocanu JD, Yip KW, Skliarenko J, Shi W, Busson P, Lo KW, Bastianutto C, Liu FF. Imaging and modulating antisense microdistribution in solid human tumour models. Cl Cancer Res. 13(19):5935-5941, 2007.
Maynard MA, Evans AJ, Shi W, Kim WY, Liu FF, Ohh M. Dominant-negative HIF-3 alpha 4 suppresses VHL-null renal cell carcinoma progression. Cell Cycle. 6(22):2810-2816, 2007.
Bastianutto C, Mian A, Symes J, Mocanu J, Alajez N, Sleep G, Shi W, Keating A, Crump M, Gospodarowicz M, Medin J Minden M, Liu FF. Local radiotherapy induces homing of hematopoietic stem cells to the irradiated bone marrow. Cancer Res. 67(21):10112-10116, 2007.
Shi W, Bastianutto C, Li A, Perez-Ordonez B, Ng R, Chow KY, Zhang W, Jurisica I, Bayley A, Kim J, O’Sullivan B, Siu L, Chen E, Liu FF. Multiple dysregulated pathways in nasopharyngeal carcinoma revealed by gene expression profiling. Int J Cancer. 119(10):2467-2475, 2006.
Yip KW, Mao X, Au PYB, Hedley DW, Chow S, Dalili, Mocanu JD, Bastianutto C, Schimmer A, Liu FF. Benzethonium chloride: A novel anticancer agent identified utilizing a cell-based small molecule screen. Cl Cancer Res. 12(18): 5557-5569, 2006.
Yip KW, Ito E, Mao X, Au PYB, Hedley DW, Mocanu JD, Bastianutto C, Schimmer A, Liu FF. Potential utility of alexidine dihydrochloride as an apoptosis-promoting anticancer agent. Mol Cancer Ther. 5(9):2234-2240, 2006.
Yip KW, Shi W, Pintilie M, Martin JD, Mocanu JD, Wong D, MacMillan C, Gullane P, O’Sullivan B, Bastianutto C, Liu FF. Prognostic significance of the Epstein-Barr Virus, p53, Bcl-2, and survivin in nasopharyngeal cancer. Cl Cancer Res. 12(19):5726-5732, 2006.
Bachtiary B, Boutros PC, Pintilie M, Shi W, Bastianutto C, Li JH, Schwock J, Zhang W, Penn LZ, Jurisica I, Fyles A, Liu FF. Gene expression profiling in cervical cancer: an exploration of intratumor heterogeneity. Cl Cancer Res. 12(19): 5632-5640, 2006.
Kim R, Peters M, Shi W, Pintilie M, DeLuca C, Liepa J, Zhou L, Snow B, Binari RC, Manoukian A, Liu FF, Tsao MS, Mak TW. DJ-1, a novel regulator of the tumor suppressor PTEN. Cancer Cell. 7(3):263-273, 2005.
Au PYB, Martin N, Chau H, Moemeni B, Chia M, Liu FF, Minden M, Yeh WC. The oncogene PDGF-B provides a key switch from cell death to survival induced by TNF. Oncogene. 24(19):3196-3205, 2005.
Yip KW, Mocanu JD, Au PYB, Sleep GT, Huang D, Busson P, Yeh WC, Gilbert R, O’Sullivan B, Gullane P, Bastianutto C, Liu FF. Combination bcl-2 antisense and radiation therapy for nasopharyngeal cancer. Cl Cancer Res. 11(22):8131-8144, 2005.
Ma N, Szmitko P, Brade A, Chu I, Lo A, Woodgett J, Klamut H, Liu FF. Kinase-dead PKB gene therapy combined with hyperthermia for human breast cancer. Cancer Gene Therapy. 11(1):52-60, 2004.
Li A, Ng E, Shi W, Lee A, Chia M, Liu T-J, Huang D, O’Sullivan B, Gullane P, Liu FF. Potential efficacy of p16 gene therapy for EBV-positive nasopharyngeal carcinoma. Int J Cancer. 110(3):452-458, 2004.
Chia MC, Shi W, Li JH, Sanchez O, Strathdee CA, Huang D, Busson P, Klamut HJ, Liu FF. A conditionally replicating adenovirus for nasopharyngeal carcinoma gene therapy. Mol Therapy. 9(6):804-17, 2004.
Millar BA, Kerba M, Youngson B, Lockwood G, Liu FF. The potential role of breast conservation surgery and adjuvant breast radiation for adenoid cystic carcinoma of the breast. Breast Cancer Research and Treatment. 87(3):225-232, 2004.
Yip KW, Li A, Li JH, Shi W, Chia MC, Al Rashid S, Mocanu J, Louie A, Sanchez O, Huang D, Busson P, Yeh W-C, Gilbert R, O’Sullivan B, Gullane P, Liu FF. Potential utility of BimS as a novel apoptotic therapeutic molecule. Mol Therapy. 10(2):533-544, 2004.
Mocanu JD, Moriyama EH, Chia MC, Li JH, Yip KW, Huang DP, Bastianutto C, Wilson BC, Liu FF. Combined in vivo bioluminescence and fluorescence imaging for cancer gene therapy. Mol Imaging. 3(4):352-355, 2004.
Shi W, Zhang XH, Ma N, Pintilie M, Miller N, Banerjee D, Tsao M, Mak T, Fyles A, Liu FF. Dysregulated PTEN-PKB and negative receptor status in human breast cancer. Int J Cancer. 104(2):195-203, 2003.
Brade AM, Ngo D, Szmitko P, Ngo D, Liu F, Klamut HJ. Heat-directed suicide gene therapy for breast cancer. Cancer Gene Therapy. 10(4):294-301, 2003.

Loss of p16 expression has prognostic significance in human nasopharyngeal carcinoma

Heat-directed tumour cell fusion

Limitation of conventional two dimensional radiation therapy planning in nasopharyngeal carcinoma

Lee A, Li JH, Shi W, Li A, Ng E, Liu TJ, Klamut HJ, Liu FF. p16 gene therapy: A potentially efficacious modality for nasopharyngeal carcinoma. Mol Cancer Ther. 2(10):961-969, 2003.
Li JH, Shi W, Chia M, Sanchez-Sweatman O, Siatskas C, Huang D, Busson P, Klamut HJ, Yeh W-C, Richardson C, O’Sullivan, Gullane P, Neligan P, Medin J, Liu FF. Efficacy of targeted FasL in nasopharyngeal carcinoma. Mol Therapy. 8(6):964-973, 2003.
Howard PL, Chia M, Del Rizzo S, Liu FF, Pawson T. Re-directing tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins. Proc. Natl. Acad. Sci. USA. 100(2):11267-11272, 2003.
Coleman CN, Stone HB, Alexander GA, Barcellos-Hoff MH, Bedford JS, Bristow RG, Dynlacht JR, Fuks Z, Gorelic LS, Hill RP, Joiner MC, Liu FF, McBride WH, McKenna WG, Powell SN, Robbins ME, Rockwell S, Schiff PB, Shaw EG, Siemann DW, Travis EL, Wallner PE, Wong RS, Zeman EM. Education and training for radiation scientists: radiation research program and American Society of Therapeutic Radiology and Oncology Workshop, Bethesda, Maryland, May 12-14, 2003. Rad Res. 160(6):729-737, 2003.
Liu FF, O’Sullivan B. In regard to Su and Wang: prognostic value of Chinese race in nasopharyngeal cancer. IJROBP 2002;54:752–758. Int J Radiat Oncol Biol Phys. 57(2): 593, 2003.
Shi W, Pataki I, MacMillan C, Pintilie M, Payne D, O’Sullivan B, Cummings BJ, Warde P, Liu FF. Molecular pathology parameters in human nasopharyngeal carcinoma. Cancer. 94(7):1997-2006, 2002.
Li JH, Chia M, Shi W, Ngo D, Strathdee C, Huang D, Klamut HJ, Liu FF. Tumor-targeted gene therapy for nasopharyngeal carcinoma. Cancer Res. 62(1):171-178, 2002.
Tsao MN, Tsang RW, Liu FF, Panzarella T, Rotstein L. Radiotherapy management for squamous cell carcinoma of the nasal skin: The Princess Margaret Hospital experience. Int J Radiat Oncol Biol Phys. 52(4):973-979, 2002.
Paisley S, Warde P, O’Sullivan B, Waldron J, Gullane P, Payne D, Liu FF, Bayley A, Ringash J, Cummings BJ. Results of radiotherapy for primary subglottic squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 52(5):1245-1250, 2002.
Liu FF. Novel gene therapy approach for nasopharyngeal carcinoma. Sem Cancer Biol. 12(6):505-515, 2002.
Warde P, O’Sullivan B, Aslanidis J, Kroll B, Lockwood G, Waldron J, Payne D, Bayley A, Ringash J, Kim J, Liu FF, Maxymiw W, Sprague S, Cummings BJ. A Phase III placebo controlled trial of oral pilocarpine in patients undergoing radiation therapy for head and neck cancer. Int J Radiat Oncol Biol Phys. 54(1):9-13, 2002.
Chow E, Payne D, O’Sullivan B, Pintilie M, Liu FF, Waldron J, Warde P, Cummings BJ. Radiotherapy alone in patients with advanced nasopharyngeal cancer: Comparison with an Intergroup Study. Is combined modality treatment really necessary? Radiother Oncol. 63(3):269-274, 2002.
Qi V, Weinrib L, Ma N, Li JH, Klamut H, Liu FF. Adenoviral p53 gene therapy promotes heat-induced apoptosis in a nasopharyngeal carcinoma cell line. Int J Hyperthermia. 17(1):38-47, 2001.
Quon H, Cummings BJ, Liu FF. Potential molecular prognostic markers in head/neck squamous cell carcinomas. Head & Neck. 23(2):147-159, 2001.
Spayne JA, Warde P, O’Sullivan B, Payne D, Liu FF, Waldron J, Gullane P, Cummings BJ. Carcinoma-in-situ of the glottic larynx: results of treatment with radiation therapy. Int J Radiat Oncol Biol Phys. 49(5):1235-1238, 2001.
Kirkbride P, Liu FF, O’Sullivan B, Payne D, Warde P, Gullane P, Pintilie M, Keane TJ, Cummings BJ. Outcome of curative management of malignant tumours of the parotid gland. J Otolaryngology. 30(5):271-279, 2001.
Ma N, Jing J, Lu F, Woodgett J, Liu FF. The potential role of PKB in mediating heat sensitivity in a human breast cancer cell line. Int J Radiat Oncol Biol Phys. 50(4):1041-1050, 2001.
Weinrib L, Li JH, Donovan J, Huang D, Liu FF. Cisplatin chemotherapy plus adenoviral p53 gene therapy in EBV-positive and negative nasopharyngeal carcinoma. Cancer Gene Therapy. 8(5):352-360, 2001.
Lax S, Chia M, Busson P, Klamut H, Liu FF. Adenovirus-p53 gene therapy in human nasopharyngeal carcinoma xenografts. Radiother Oncol. 61(3):309-312, 2001.
O’Sullivan B, Warde P, Grice B, Goh C, Payne D, Liu FF, Waldron J, Bayley A, Irish J, Gullane P, Cummings BJ. The benefits and pitfalls of ipsilateral radiotherapy in carcinoma of the tonsillar region. Int J Radiat Biol Phys. 51(2):332-343, 2001.
Groome PA, Schulze K, MacKillop WJ, Grive B, Goh C, Cummings B, Hall SF, Liu FF, Payne D, Rothwell D, Waldron J, Warde P, O’Sullivan B. A comparison of published head and neck stage groups in carcinomas of the tonsillar region. Cancer. 92(6):1484-1494, 2001.
Li J-H, Huang D, Sun B-F, Middeldorp J, Takada K, Klamut HJ, Liu FF. The efficacy of ionizing radiation combined with adenoviral p53 therapy in EBV-positive nasopharyngeal carcinoma. Int J Cancer. 87(4):606-610, 2000.
Warde P, Kroll B, O’Sullivan B, Aslanidis J, Tew-George E, Waldron J, Maxymiw W, Liu FF, Payne D, Cummings B. A phase II study of Biotene in the treatment of postradiation xerostomia in patients with head and neck cancer. Support Care Cancer. 8(3):203-208, 2000.
Waldron JN, O’Sullivan B, Gullane P, Witterick I, Liu FF, Payne D, Warde P, Cummings BJ. Carcinoma of the maxillary antrum: a retrospective analysis of 110 cases. Radiother Oncol. 57(2):167-173, 2000.
Brade AM, Ngo D, Szmitko P, Li PX, Liu FF, Klamut HJ. Heat-directed gene targeting of adenoviral vectors to tumour cells. Cancer Gene Therapy. 7(12):1566-1574, 2000.

1999-1979

Li JH, Lax S, Kim J, Klamut H, Liu FF. The effects of combining ionizing radiation and adenoviral p53 therapy in nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 43(3):607-616, 1999.
Li J-H, Donovan J, Sun B-F, Liu FF. Inhibition of protein kinase C activity promotes heat-induced apoptosis in RIF-1, but not in TR-4 cells. Int J Radiat Biol. 75(7):903-911, 1999.
Lax SA, Liu FF. Tumor suppressor gene therapy. University of Toronto Medical Journal. 76:86-92, 1999.
Samuels TH, Liu FF, Yaffe M, Haider M. Gestational breast cancer. Can Assoc Radiol J. 49(3):172-180, 1998.
Warde P, O’Sullivan B, Bristow R, Panzarella T, Keane TJ, Gullane PJ, Witterick IP, Payne D, Liu FF, McLean M, Waldron J, Cummings BJ. T1/T2 glottic cancer managed by external beam radiotherapy: The influence of pretreatment Hemoglobin on local control. Int J Radiat Oncol Biol Phys. 41(2):347-353, 1998.
Sun A, Liu FF, Rawlings G. Outcome in breast cancer managed without an initial axillary lymph node dissection. Radiother Oncol. 48(2):191-196, 1998.
Kim CS, Hill RP, Kumaradas JC, Irvine R, Liu FF, Sherar MD. Effect of simultaneous pulsed hyperthermia and pulsed radiation treatment on survival of SiHa cells. Int J Hyperthermia. 14(6):573-81, 1998.
Waldron JN, O’Sullivan B, Warde P, Gullane P, Liu FF, Payne D, Cummings. Ethmoid sinus cancer: twenty-nine cases managed with primary radiation therapy. Int J Radiat Oncol Biol Phys. 41(2):361-369, 1998.
Pass B, Wood ER, Liu FF, McLean M, Aldrich JE. High radiation doses from radiotherapy measured by electron spin resonance in dental enamel. Radiation Protection Dosimetry. 76(4):239-247, 1998.
Li JH, Liu FF. Intracellular pH and heat sensitivity in two human cancer cell lines. Radiother Oncol. 42(1):69-76, 1997.
Li JH, Li P, H Klamut, Liu FF. Cytotoxic effects of Ad5CMV-p53 expression in two human nasopharyngeal carcinoma cell line. Cl Cancer Res. 3(4)507-514, 1997.
Sherar M, Liu FF, Pintilie M, Levin W, Hunt J, Hill R, Hand J, Vernon C, van Rhoon G, van der Zee J, Gonzalez Gonzalez D, van Dijk J, Whaley J, Machin D. Relationship between thermal dose and outcome in thermoradiotherapy treatments for superficial recurrences of breast cancer: Data from a Phase III trial. Int J Radiat Oncol Biol Phys. 39(2): 371-380, 1997.
Liu FF, Diep K, Tannock IF, Hill RP. The effect of heat on Na+/H+ antiport function and survival in mammalian cells. Int J Radiat Oncol Biol Phys. 34(3): 623-634, 1996.
Liu FF, Miller N, Levin W, Zanke B, Cooper B, Henry M, Sherar MD, Pintilie M, Hunt JW, Hill RP. The potential role of HSP70 as an indicator of response to radiation and hyperthermia treatments for recurrent breast cancer. Int J Hyperthermia. 12(2):197-208, 1996.
Liu FF, Sherar MD, Hill RP. The relationship between intracellular pH and heat sensitivity in a thermoresistant cell line. Radiat Res. 145(2):144-149, 1996.
Zanke BW, Boudreau K, Rubie EA, Liu FF, Woodgett JR. The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat. Curr Bio. 6(5):606-613, 1996.
Vernon CC, Hand JW, Field SB, Machin D, Whaley JB, van der Zee J, van Putten WL, van Rhoon GC, van Dijk JD, González González D, Liu FF, Goodman P, Sherar M. Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: results from five randomized controlled trials. International Collaborative Hyperthermia Group. Int J Radiat Oncol Bio Phys. 35(4):731-744, 1996.
Kwan W, Liu FF, Banerjee D, Rotstein L, Tsang R. Concurrent papillary and squamous carcinoma in a thyroglossal duct cyst: a case report. Can J Surgery. 39(4):328-332, 1996.
Liu FF, Diep K, Hill RP. The relationship between thermosensitivity and intracellular pH in cells deficient in Na+/H+ antiport function. Radiother Oncol. 40(1):75-83, 1996.
McLachlan SA, Erlichman C, Liu FF, Miller N, Pintilie M. Male breast cancer: an 11 year review of 66 patients. Breast Cancer Res Treat. 40(3):225-230, 1996.
Liu FF, Bezjak A, Levin W, Cooper B, Pintilie M, Sherar MD. Assessment of palliation in women with recurrent breast cancer. Int J Hyperthermia. 12(6):825-826, 1996.
Liu FF, Lee C, Li, JH. Influence of heat on Na(+)-dependent HCO3-/Cl- exchanger function in a thermoresistant cell line. Int J Radiat Biol. 70(4):481-489, 1996.
Liu FF, Rotstein L, Davison A, Pintilie M, O’Sullivan B, Payne D, Warde P, Cummings BJ. Benign parotid adenomas: a review of the Princess Margaret Hospital experience. Head & Neck. 17(3):177-183, 1995.
Levin W, Sherar MD, Cooper B, Hunt JW, Hill RP, Liu FF. The effect of vascular occlusion on tumour temperatures during superficial hyperthermia. Int J Hyperthermia. 10(4):495-505, 1994.
Hopkins ML, McGowan TS, Rawlings G, Liu FF, Fyles AW, Yeoh JL, Manchul L, Levin W. Phylloides tumor of the breast: a report of 14 cases. J Surg Oncol. 56(2):108-112, 1994.
Tsang RW, Liu FF, Wells W. Lentigo maligna of the head and neck. Results of treatment by radiotherapy. Arch Derm. 130(8):1008-1012, 1994.
Sherar MD, Clark H, Cooper B, Kumaradas J, Liu FF. A dynamic microwave array filter for use with single element waveguide applicators. Int J Hyperthermia. 10(5):723-731, 1994.
Sherar MD, Liu FF, Newcombe DJ, Levin W, Cooper B, Taylor WB, Hunt JW. Beam shaping for microwave waveguide hyperthermia applicators. Int J Radiat Oncol Biol Phys. 25(5):849-857, 1993.
Esche B, Liu FF, Raaphorst P, Corry P, Overgaard J. Hyperthermia: Development and Directions. Annals of the Royal College of Physicians and Surgeons of Canada. 6:391-392, 1993.
Liu FF, Keane T, Davidson J. Primary carcinoma involving the petrous temporal bone. Head & Neck. 15(1):39-43, 1993.
Cerezo L, Liu FF, Tsang R, Payne D. Squamous cell carcinoma of the lip: Analysis of the Princess Margaret Hospital Experience. Radiother Oncol. 28(2):142-147, 1993.
Kirkbride P, Liu FF, Wax M. Radiation-induced hearing impairment--a pilot study in patients treated for malignant parotid tumours. Br J Radiology. 65(777):833-835, 1992.
Liu FF, Maki E, Payne D, Fitzpatrick P. A management approach to incompletely excised basal cell carcinomas of skin. Int J Radiat Oncol Biol Phys. 20(3):423-428, 1991.
Maxymiw W, Wood R, Liu FF. Postradiation dental extractions without hyperbaric oxygen. Oral Med Oral Surg Oral Path. 72(3):270-274, 1991.
Valdagni R, Liu FF. Evaluating radiation in combination with hyperthermia trials: the importance of clinical and technical parameters. Tumori. 76(2):205-211, 1990.
Bell RS, O’Sullivan BO, Liu FF, Powell J, Langer F, Fornasier VL, Cummings BJ, Miceli PN, Hawkins N, Quirt I, Warr D. The surgical margin in soft-tissue sarcoma. J Bone Joint Surgery. 71(3):370-375, 1989.
Kapp DS, Prionas SD, Fessenden P, Liu FF, Lee ER, Lohrbach AW. Bladder cooling in patients treated with regional hyperthermia of the pelvis using an annular phased array. Int J Radiat Oncol Biol Phys. 14(6):1307-1310, 1988.
Valdagni R, Liu FF, Kapp D. Important prognostic factors influencing outcome of combined radiation and hyperthermia. Int J Radiat Oncol Biol Phys. 15(4):959-972, 1988.
Liu FF, Clark RM. Primary lymphoma of the breast. Clinical Radiology. 37(6):567-570, 1986.
Liu FF, Love KR, Kutas G. Pneumocystis carinii - review of Toronto General Hospital experience. University of Toronto Medical Journal. 1980.
MacLeod SM, Giles HG, Bengal B, Liu FF, Sellers EM. Age and gender-related differences in Diazepam pharmacokinetics. J Clin Pharmacol. 19(1):15-19, 1979.