Arthur Worthington
Research
Technician
B.Sc.
University of Toronto (1973)
Research Interests
Ultrasound imaging; Ultrasonic properties of tissue; Ultrasound heating; Phantom
creation; Experimental design and construction; Machining; Temperature measurement;
Programming to control equipment, Collecting and processing data.
Publications
Journal
Papers
W B. Taylor, J.W. Hunt, F.S. Foster, R. Blend, A. Worthington,
S.L.
Brown, X.L. Li, H.H. Pai, A.E. Worthington, R.P. Hill, J.W.
Hunt,
J.W. Hunt, R.J.
Lalonde, H. Ginsberg, S. Urchuk, A. Worthington
R.J. Lalonde, A. Worthington, J.W. Hunt, Field
Conjugate Acoustic Lenses for Ultrasound Hyperthermia Treatments,
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control 40(5):
592-602, 1993
M.C. Kolios,
M.D. Sherar, A.E. Worthington, J.W. Hunt
J.W. Hunt, A.E. Worthington, A.T. Kerr, The
Subtleties of Ultrasound Images of an Ensemble of Cells: Simulation from Regular
and More Random Distributions of Scatterers,
Ultrasound in Medicine and Biology 21(3): 329-351, 1995.
Z.Q. Jia, A.E. Worthington, R.P. Hill, J.W. Hunt, The
Effects of Artery Occlusion on Temperature Homogeneity under Hyperthermia
in Rabbit Kidneys
in Vivo,
International Journal of Hyperthermia 13(1): 21-37, 1997.
A.E. Worthington,
J. Thompson, A.M. Rauth and J.W. Hunt, Mechanism
of Ultrasound-Enhanced Porphyrin Cytotoxicity. Part I: A Search for Free Radical
Effects,
Ultrasound in Medicine and Biology 23(7): 1095-1103, 1997.
M.R. Gertner, A.E.
Worthington, B.C. Wilson, M.D. Sherar, Ultrasound
Imaging of Thermal Therapy in in Vitro Liver, Ultrasound in Medicine
and Biology 24(7): 1023-1032, 1998.
M.C. Kolios, A.E.
Worthington, M.D. Sherar, J.W. Hunt, Experimental
Evaluation of Two Simple Thermal Models Using
Transient Temperature Analysis,
Physics in Medicine and Biology 43(11): 3325-3340, 1998.
M.C. Kolios, A.E.
Worthington, D.W. Holdsworth, M.D. Sherar, J.W. Hunt, An
Investigation of the Flow Dependence of Temperature Gradients Near Large Vessels
during Steady State and Transient
Tissue Heating,
Physics in Medicine and Biology 44(6): 1479-97, 1999
A.E. Worthington,
M.D. Sherar, Changes
in the Ultrasound Properties of Porcine Kidney During Heating, Ultrasound
in Medicine and Biology, 27(5): 673-682, 2001
J.W. Hunt, A. E. Worthington, A. Zuan, M.C. Kolios, G.J.
Czarnota, M.D. Sherar, A
Model Based upon Pseudo Regular Spacing of Cells Combined with the Randomization
of the Nuclei
can Explain the Significant Changes in High-Frequency Ultrasound Signals during
Apoptosis,
Ultrasound in Medicine and Biology 28(2): 217-226, 2002
A.E. Worthington,
J. Trachtenberg, M.D. Sherar
Conference
Papers
J.W. Hunt, R.P. Hill, A. Worthington, High Powered Ultrasound
Sources Using Conical Geometries Used for
G. Lockwood, A. Worthington, J.W. Hunt, Deep Heating
Using Focussed, Scanning Ultrasound Beams, 48th Annual Meeting of the
Canadian Association of Radiologists, Toronto, June 1985.
M. Bernstein, R. D'Silva, S.L. Brown, A. Worthington, J.W.
Hunt. Inductive Radiofrequency Heating in a Rat Brain Tumour Model. 6th International Congress on Brain Tumour
Research and Therapy, Asheville,
North Carolina, October 1985.
G. Lockwood, A.
Worthington, J.W. Hunt, Ultrasound Hyperthermia Using Conically
Focussed Scanning Transducers, 34th Annual Meeting of the Radiation Research
Society, Las Vegas, April 1986.
J.W. Hunt, M. Bernstein, L. Heinzl, A. Worthington, J.A.
Glenn, Combination of RF Inductive Heating and Interstitial 155I
Brachytherapy in a Rat Brain Tumour
Model,
8th International Congress of the Radiation Research Society, Edinburgh, July
1987.
J.W. Hunt, A.
Worthington, S. Urchuk, M. Bernstein, Theoretical and Experimental
Assessment of Short Hyperthermia Treatments
J.W. Hunt, A. Worthington, S. Urchuk, Evaluate Short
Treatment Times Combined with High Temperature Protocols by Using
J.W. Hunt, H. Ginsberg,
R. Lalonde, S. Urchuk, A. Worthington, Rapid Heating:
Critical Theoretical Assessment of Thermal Dradients Found in
Hyperthermia Treatments.
37th Annual Meeting of the Radiation Research Society and 9th Annual Meeting
of the North American Hyperthermia Group, Seattle, March 1989.
R. Lalonde, A. Worthington, J.W. Hunt, Modelling Temperature
Distributions Produced by Ultrasound Phased Arrays,
R.J. Lalonde,
A. Worthington, J.W. Hunt
R.J. Lalonde, A. Worthington, J.W. Hunt, Hyperthermia:
Field Conjugate Acoustic Lenses for Deep Heating, 12th IEEE Engineering
in Medicine and Biology Conference, pp 235-236, Philadelphia,
R.J.
Lalonde, A. Worthington, J.W. Hunt, Field Conjugate Acoustic
Lenses for Hyperthermia, 13th IEEE Ultrasonics Conference,
Orlando, December 1991.
R.J. Lalonde, A.E.
Worthington, J.W. Hunt, Phase Conjugative Lens for Hyperthermia
Treatments, 34th Annual Meeting of the American Association of Physicists
in Medicine, Calgary, Canada, August 1992.
Z.Q. Jia, A.E.
Worthington, J.W. Hunt, The Effects of Arterial Occlusion on
the Temperature Distribution under Hyperthermia
in Animal Kidneys in Vivo,
41st Annual Meeting of the Radiation Research Society, Dallas, 1993.
Z.Q. Jia, A.E.
Worthington, R.P. Hill, J.W. Hunt, The Temperature Distribution
During Heating of a Kidney Phantom in vitro: The
Effect of "Blood Flow" and use of a Focussed Ultrasound Beam,
14th Annual Meeting of the North American Hyperthermia Society, Nashville,
1994.
M.C. Kolios, A.E.
Worthington, J.W. Hunt, Modelling Thermally Signifigant Vessels
during Hypethermia, 15th Annual Meeting of the North American Hyperhermia
Society, San Jose, 1995.
M.C. Kolios, M.D.
Sherar, A.E. Worthington, J.W.Hunt
J.W. Hunt, A.Y. Xuan, E. Seto, A.E. Worthington, M.C. Kolios,
M.D. Sherar, High Intensity Focussed Ultrasound Studies: Optimization
of the Beams Near the Skin During Multiple
Lesion Treatments.
16th Annual Meeting of the North American Hyperthermia Society, Providence,
May 1997
M.C. Kolios, M.D.
Sherar, A.E. Worthington, J.W. Hunt,
A.E. Worthington,
J. Thompson, R. Lalonde, M. Patterson, A.M. Rauth, J.W. Hunt, Mechanism
of Ultrasound Enhanced Porphyrin Cytotoxicity: Free Radial and Hematoporphyrin
Effects,
IEEE International Ultrasonics Symposium, pp 1349-1352, Toronto 1997.
M. Gertner, B.C.
Wilson, A.E. Worthington, M.D. Sherar. Ultrasound Properties
and Images of Ex-vivo Liver During Thermal Therapy, IEEE
International Ultrasonics Symposium, pp 1352-1356, Toronto 1997.
J.W. Hunt, A.Y.
Xuan, E. Seto, A.E. Worthington, L. Chen, M.C. Kolios, M.D.
Sherar, New Acoustic Beams Designed for Rapid Lesion Formation: Limitations
Near the Skin during Multiple
Lesion Treatments,
IEEE International Ultrasonics Symposium, pp 1373-1376, Toronto 1997.
M.D. Sherar, M.
Gertner, A.E. Worthington, P.D. Bevan, R. Rendon, M. Jewett,
M. Pop, X. Wu, Changes in Ultrasound Properties of Kidney Due to Heating:
Implications for Ultrasound Thermal Therapy Planning
and Monitoring,
19th Annual Meeting of the North American Hyperthermia Society, San Juan,
Puerto Rico, April 2001.
Contact
Princess Margaret Hospital, Room 8-326
610 University Avenue
Toronto, Ontario
CANADA M5G 2M9
Phone: (416) 946-4501 x5048
Fax: (416) 946-2086
e-mail: worthing@uhnres.utoronto.ca
Last updated: July 15, 2004