Contact info
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Liu Laboratory
University Health Network
Princess Margaret Cancer Centre
101 College Street, 11th floorToronto, Ontario, Canada, M5G 1L7
News
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April 2022
Congratulations to Dr. Fei-Fei Liu who was appointed as the 2022-2023 Chair-Elect of the American Association for Cancer Research (AACR) Radiation Science and Medicine Research (RSM) Working Group.
Dr. Jennifer Kwan received the 2022 Institute of Medical Science Siminovitch-Salter Award, which is awarded annually to a graduating IMS doctoral student who has made outstanding scholarly contributions!
January 2022
Dr. Fei-Fei Liu discusses 3 life-altering aftereffects of cancer therapy, and the exciting clinical developments and research findings from her lab that aims to help patients live free from the aftermath of their cancer therapies at TEDxUofT: Momemtum - "The World Beyond Cancer Survivorship". Watch the video here.
July 2021
Congratulations to Dr. Jennifer Kwan on her successful PhD defense!
Madi Hossack was awarded a Summer Undergraduate Studentship from the University of Toronto's Undergraduate Research Opportunities Program. These awards were given to the summer students with the highest GPA’s in the 2021 summer program!
February 2021
Congratulations to Drs. Fei-Fei Liu and Jennifer Kwan on their publication, "Elevation in viral entry genes and innate immunity compromise underlying increased infectivity and severity of COVID-19 in cancer patients" in Sci Rep. Read the feature on UHN News to learn more.
February 2020
Petra Famiyeh is featured on the UofT Faculty of Medicine's newsletter for Black History Month! Read about her experiences on education and lymphedema research here.
January 2020
Congratulations to Drs. Fei-Fei Liu, Xiao Zhao, Jennifer Kwan and Ken Yip on their recent publication, "Targeting Metabolic Dysregulation for Fibrosis Therapy" in Nature Reviews Drug Discovery.
Dr. Fei-Fei Liu delivered an inspirational keynote on Jan 26 to over 600 science and engineering students from across North America at UofT’s 2020 WISE (Women in Science and Engineering) National Conference. Watch the video here.
News Archive
Welcome
The Liu Laboratory is a leader in head and neck cancer translational medicine at the Princess Margaret Cancer Centre/Ontario Cancer Institute, the largest oncology treatment and research facility in Canada. The major goal of the lab is to innovate discoveries, which will benefit cancer patients. Our research is conducted with the highest standards of scientific rigour and integrity, in a collaborative manner, guided by mutual respect, courtesy, and consideration. In addition, the lab leads projects in breast and cervical cancer.
Our Research
We focus on several aspects of translational molecular oncology, including the development of biomarkers for head and neck cancers, high-throughput screens to identify novel anti-cancer therapeutics, and stem cell regenerative therapy. Using DNA, RNA, and protein extracted from diagnostic human cancer samples, we are in the process of conducting multi-omic global expression analyses. Preliminary data are very promising, and in addition to identifying multi-dimensional predictive/prognostic signatures for improving cancer patient management, we are also studying their related pathways and biological functions in preclinical models of human cancers. Automated robotic screens are being used to identify corresponding novel anti-cancer compounds, and characterization of these potential new therapeutics is underway. We are also interested in understanding how adipose derived stem cells may aid in tissue regeneration after treatment with ionizing radiation. Finally, our lab is working to unravel the mechanisms and identify therapeutic strategies of radiation fibrosis and lymphedema; two important late normal tissue toxicities with significant functional morbidity.