The Sherar Lab for Image-Guided Minimally-Invasive Therapy
Group photo taken with a FLIR ThermaCAM SC2000 thermal camera.
Our laboratory is working on the development of image guided minimally invasive therapies (MIT) for cancer treatment, with foci in thermal therapy and ultrasound image guidance. This work is based on the broad hypothesis that image guided MIT's can achieve equivalent or better efficacy and improved complication profiles than standard treatments for some solid tumour sites.
Specifically, we are currently engaged in clinical trials in microwave thermal therapy for prostate cancer, radiofrequency thermal therapy for kidney cancer and the use of high frequency ultrasound imaging to monitor the process of apoptosis as an early surrogate marker for tumour response to radiation or chemotherapy in basal cell carcinoma and other superficial cancers. Earlier, laboratory stage work on the development of a novel, completely non-invasive ultrasound image guided ultrasound thermal therapy system with application to renal cancer is in progress. Another main area of focus is the development of treatment planning systems for MIT's including thermal therapy and photodynamic therapy.
Graduate students are involved
in all aspects of the research cycle from, theoretical analysis and modelling,
technology development and evaluation to animal and finally human trials.
Search PubMed for Publications from this lab.
|Tissue Property Measurement||Principal Investigator|
|Mihaela Pop||Dr. Michael Sherar|
|Mathematical Modelling||Dr. Gregory Czarnota|
|and Treatment Planning||Dr. John Hunt|
|Sean Davidson||Dr. Michael Jewett|
|Dr. J. Carl Kumaradas||Dr. Michael Kolios|
|Mihaela Pop||Dr. John Trachtenberg|
|Wu Xia||Dr. William Whelan|
|Applicator Development and Testing||Graduate Students|
|Sean Davidson||Claire McCann|
|Wu Xia||Claudia Strobele|
|Image-Based Treatment Monitoring|
|Dr. Mark Gertner||Research Staff|
|Peter Bevan||Sean Davidson|
|Claudia Strobele||Dr. Mark Gertner|
|High Frequency Ultrasound Imaging|
|Clinical Trials||Dr. J. Carl Kumaradas|
|Sean Davidson||Mihaela Pop|
|Dr. Mark Gertner||Ralph Baddour|
General inquiries about the research conducted in this lab: Sean Davidson. For more information on other areas of research, please visit the University Health Network (UHN) and UHN Research web sites. For information on pursuing graduate studies, contact the Department of Medical Biophysics in the University of Toronto. Please Note: The University Health Network does not make appointments nor provide medical advice, consultations or referrals over the Internet. Please consult your regular physician regarding such matters.
© 2003 Sherar Lab, University Health Network
Last updated: February 10, 2004